- IN STOCK
- product code: S012
100 µg Stored at -20 to -80 oC
This product contains the receptor binding domain (RBD) of the spike glycoprotein protein (S-protein) of the SARS-CoV corona virus (2002). Infection with this virus causes severe acute respiratory syndrome. The spike protein is the common target for neutralizing antibodies and vaccines. The Spike protein contains two subunits, S1 and S2. Subunit S1 contains a receptor binding domain (RBD), which is responsible for recognizing and binding with the cell surface receptor ACE-2 (products A004 and A005). S2 subunit contains other basic elements needed for the membrane fusion and trimerisation. The protein is produced in HEK293 cells and contains a C-terminal, TEV-protease cleavable Fc-AVI-tag, which can be used for in vitro site-specific biotinylation, using the BirA enzym. It was purified to homogeneity (figure 1). The calculated molecular weight of recombinant SARS-CoV-RBD-(TEV-Fc-AVI)C is 104 kDa.
Limitations of use:
The product is not for use in humans.
The product can only be used for internal research and development.
The product can not be used in any commercial activity (commercial use includes, but is not limited to activities for third paries).
The product can not be resold.
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