Product description:
This product contains the receptor binding domain (RBD) of the spike glycoprotein protein (S-protein) of the SARS-CoV corona virus (2002). Infection with this virus causes severe acute respiratory syndrome. The spike protein is the common target for neutralizing antibodies and vaccines. The Spike protein contains two subunits, S1 and S2. Subunit S1 contains a receptor binding domain (RBD), which is responsible for recognizing and binding with the cell surface receptor ACE-2 (products A004 and A005). S2 subunit contains other basic elements needed for the membrane fusion and trimerisation. The protein is produced in HEK293 cells and does not contain a tag. It was purified to homogeneity (figure 1). The calculated molecular weight of recombinant SARS-CoV-RBD is 23.4 kDa.