- IN STOCK
- product code: S003A
Recombinant Syndecan-1-(his)C, human.
The protein contains a C-terminal his tag and is produced in HEK293E cells and purified to homogeneity.
This protein a type I membrane heparan sulphate proteoglycan. Syndecan-1 is involved in cell prolifiration, cell migration, and cell-matrix interactions. Altered syndecan-1 expression has been observed in several tumor types.
Reference sequences: NM_002997, NP_002988, Swiss-prot P18827.
Alternative names: syndecan, SDC, SYND1, CD138, Heparan sulfate proteoglycan fibroblast growth factor receptor.
Gene ID: 6382.
The ecto-domain of human syndecan-1, residues 21 - 254 was over-expressed in HEK293EBNA1 cells and purified to homogeneity. The protein has 5 potential O-linked glycosylation sites, 1 potential N-linked glycosylation site and 1 phosphorylated serine residue. The protein of this product has a higher molecular weight compared to S003B, see figure 1, suggesting a higher degree of glycosylation. The protein contains a C-terminal hexahistidine tag. The calculated molecular weight without glycosylation of recombinant human syndecan-1, residues 21 - 254 including hexahistidine tag, is 25.8 kDa. Each vial contains 100 µg Syndecan-1 at 1,04 mg/ml.