- IN STOCK
- product code: A004
100 µg Stored at -20 to -80 oC
Human ACE-2 (angiotensin-converting enzyme 2) belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angioten- kDa sin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus). The protein is produced in HEK293 cells and contains a C-terminal, TEV-protease cleavable Fc-tag. It was purified to homogeneity (figure 1). The calculated molecular weight of recombinant hACE-2-(TEV-Fc)C is 193.9 kDa.
Limitations of use:
The product is not for use in humans.
The product can only be used for internal research and development.
The product can not be used in any commercial activity (commercial use includes, but is not limited to activities for third paries).
The product can not be resold.
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